2008.09.22. Guide for Nucleic Acid Exam

September 22, 2008

Based on Boyer, Rodney (2006) Concepts in Biochemistry 3rd Edition. Hoboken, NJ: John Wiley & Sons.

Chapter 10: Nucleic Acids and DNA

  1. RNA and DNA Chemical Structures
  2. DNA Structural Elements
  3. RNA Structural Elements
  4. Cleavage of DNA and RNA by Nucleases
  5. Nucleic Acid-Protein Complexes

Chapter 11. Biosynthesis of DNA and RNA: Replication and Transcription

  1. Replication of DNA
  2. Action of DNA Polymerases
  3. DNA Damage and Repair–not in detail
  4. Synthesis of RNA
  5. Post-transcriptional Modification of RNA
  6. Base Sequences in DNA

Chapter 12. Protein Synthesis and the Genetic Code

  1. The Process of Protein Synthesis
  2. Three Stages of Protein Synthesis
  3. Post-translational Processing of Proteins (not for now, since we talked about it in proteins, but make sure you review this for the final exam)
  4. Regulation of Protein Synthesis and Gene Expression

Chapter 13. Biotechnology: Recombinant DNA and Gene Therapy

  1. Recombinant DNA Technology
  2. Preparing Recombinant DNA
  3. DNA Amplification by the Polymerase Chain Reaction
  4. Applications of Recombinant DNA Technology (skim through only for now)

Don’t forget the reports coming up later today! They will be part of the exam on Monday, September 29.

Also, check out the links and downloads page for additional enrichment– the molecular visualization links should be helpful. Too bad we don’t have time for bioinformatics in class, but you can explore some of the links on your own.

It seems that Eid is on October 2. So, please get ready to stay on September 29 til about 9 pm for the last set of reports, unless the reporters would prefer to meet up on another evening or Saturday.

See you in class!


Alberts et al., 1994 vs. The Beatles, 1969

September 2, 2008

I was trawling for images to use for an upcoming lecture when I came across Professor Larry Moran’s blog (http://sandwalk.blogspot.com/2007_03_01_archive.html), with its image of the authors of the 3rd edition of Molecular Biology of the Cell: Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, James D. Watson. His blog was commenting on the place itself where it was taken, and how it was not recognized by his students.

//sandwalk.blogspot.com/2007_03_01_archive.html of Professor Larry Moran.

Molecular Biology of the Cell 3e Authors: Alberts et al., from the back cover, taken from http://sandwalk.blogspot.com/2007_03_01_archive.html of Professor Larry Moran.

Well, I haven’t been by that place at all, and I’m nowhere near as old as Prof. Moran or the MBoC authors, but the shot looks like a riff on the much-copied, much-parodied, music classic:

The Beatles Abbey Road Album, 1969

The Beatles Abbey Road Album, 1969

Well, who do you think look better– Alberts et al. or John, Paul, George, and Ringo ? The pic just proves that scientists have a sense of pop culture and iconography. 😉 I wonder if Alberts et al. listened to the Beatles when they wrote the book.

Wala lang, naaliw lang ako. Di ko era, pero aliw pa rin.